Polycatechol Nanoparticle MRI Contrast Agents
نویسندگان
چکیده
منابع مشابه
Polycatechol Nanoparticle MRI Contrast Agents.
Amphiphilic triblock copolymers containing Fe(III) -catecholate complexes formulated as spherical- or cylindrical-shaped micellar nanoparticles (SMN and CMN, respectively) are described as new T1-weighted agents with high relaxivity, low cytotoxicity, and long-term stability in biological fluids. Relaxivities of both SMN and CMN exceed those of established gadolinium chelates across a wide rang...
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Objective(s): This study describes the preparation, biodistribution of 153Sm-DTPA-SPION after intravenous injection in rats. Materials and Methods: The chelator DTPA dianhydride was conjugated to SPION using a small modification of the well-known cyclic anhydride method. Conjugation was done at a 1: 4 (SPION: ccDTPA) molar ratio. Conjugation reaction was purified with magnetic assorting column...
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ژورنال
عنوان ژورنال: Small
سال: 2015
ISSN: 1613-6810
DOI: 10.1002/smll.201502754